Emons, Carry H. H. et al. published their research in Tetrahedron: Asymmetry in 1991 | CAS: 114746-70-2

(R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid (cas: 114746-70-2) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Safety of (R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid

A new convenient method for the synthesis of chiral C3-synthons was written by Emons, Carry H. H.;Kuster, Ben F. M.;Vekemans, Jozef A. J. M.;Sheldon, Roger A.. And the article was included in Tetrahedron: Asymmetry in 1991.Safety of (R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid This article mentions the following:

Routes are described for the facile preparation of protected optically pure D– and L-glyceric acid, e.g. I [R = Me, RR = (CH2)5], starting from D-mannitol, D-isoascorbic acid, and L-ascorbic acid. The key step is a ruthenium catalyzed oxidative cleavage of the vicinal diols, e.g. II, or the α-hydroxy acids, e.g. III. In the experiment, the researchers used many compounds, for example, (R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid (cas: 114746-70-2Safety of (R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid).

(R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid (cas: 114746-70-2) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Safety of (R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem