Downstream synthetic route of 4,5-Dimethyl-1,3-dioxol-2-one

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand 4,5-Dimethyl-1,3-dioxol-2-one reaction routes.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.37830-90-3, 4,5-Dimethyl-1,3-dioxol-2-one it is a common compound, a new synthetic route is introduced below.37830-90-3

NBS (19.58 g, 110 mmol) followed by AIBN (0.821 g, 5.00 mmol) were added to a stirred, room temperature mixture of 4,5-dimethyl-l,3-dioxol-2-one (5.70 g, 50 mmol) in benzene (300 mL) and the mixture was stirred at reflux for 1 h. Volatiles were removed.Chromatography over silicaeluting with 5-55% EtOAc/hexane afforded the desired product as a yellow oil.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand 4,5-Dimethyl-1,3-dioxol-2-one reaction routes.

Reference£º
Patent; NICOX S.A.; MERCK & CO. INC.; ALMIRANTE, Nicoletta; MANDELLI, Valentino; NICOTRA, Alessia; BIONDI, Stefano; ONGINI, Ennio; SEBHAT, Iyassu; WO2010/15447; (2010); A1;,
1,3-Benzodioxole – Wikipedia
Dioxole | C3H4O2 – PubChem