Organocatalytic enantioselective conjugate addition of 2-nitrocyclohexanone to acrylaldehyde: a concise two-step synthesis of chiral building block 1-azaspiro[4.5]decan-6-one was written by Ding, Xiao-Hua;Cui, Wei-Chen;Li, Xiang;Ju, Xuan;Liu, Dan;Wang, Shaozhong;Yao, Zhu-Jun. And the article was included in Tetrahedron Letters in 2013.Recommanded Product: 126-39-6 This article mentions the following:
A gram-scale organocatalytic enantioselective Michael addition of α-nitrocyclohexanone to acrolein has been developed, and it was successfully applied to a concise two-step synthesis of (1S)-azaspiro[4.5]decan-6-one I, a useful chiral building block for the synthesis of a variety of natural alkaloids. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Recommanded Product: 126-39-6).
2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: 126-39-6
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem