On April 10, 2014, Devkota, Kanchan; Lohse, Brian; Liu, Qing; Wang, Ming-Wei; Staerk, Dan; Berthelsen, Jens; Clausen, Rasmus Praetorius published an article.Recommanded Product: 38838-06-1 The title of the article was Analogs of the Natural Product Sinefungin as Inhibitors of EHMT1 and EHMT2. And the article contained the following:
A series of analogs of the natural product sinefungin lacking the amino acid moiety was synthesized and probed for their ability to inhibit EHMT1 and EHMT2. This study led to inhibitors, e.g. I, of methyltransferase activity of EHMT1 and EHMT2 and it demonstrates that such analogs constitute an interesting scaffold to develop selective methyltransferase inhibitors. Surprisingly, the inhibition was not competitive toward AdoMet. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Recommanded Product: 38838-06-1
The Article related to nucleoside preparation ehmt1 ehmt2 methyltransferase inhibitor sinefungin analog, ehmt1, ehmt2, sinefungin, methyltransferase inhibitors, Carbohydrates: Nucleosides and Nucleotides, Cobalamins, Riboflavin and other aspects.Recommanded Product: 38838-06-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem