On December 23, 1988, Classon, Bjoern; Liu, Zhengchun; Samuelsson, Bertil published an article.SDS of cas: 38838-06-1 The title of the article was New halogenation reagent systems useful for the mild one-step conversion of alcohols into iodides or bromides. And the article contained the following:
Three new iodination and bromination reagent systems based upon phosphines are described, in which the phosphorus containing products are readily removed from the organic phase of the reaction mixture Reactions were carried out on suitably protected carbohydrates. The halogenation reagent systems consist of iodine (or bromine), imidazole and one of the following reagents: (A); Ph2PCl, (B); (p-dimethylaminophenyl)diphenylphosphine or (C); polymer-bound triphenylphosphine. The solvent used is toluene, and the phosphorous containing products are removed from the toluene phase by extraction into an aqueous sodium carbonate or sodium hydroxide phase (A); by extraction into an aqueous hydrochloric acid (pH≈1) phase (B); and by filtration (C). Ph2PCl is com. available and halogenation reagent system (A) represents the most reactive (shorter reaction time and lower temperature), of the three systems. Yields for all systems are high. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).SDS of cas: 38838-06-1
The Article related to halogenation carbohydrate reagent system, bromination carbohydrate reagent system, iodination carbohydrate reagent system, Carbohydrates: General and other aspects.SDS of cas: 38838-06-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem