Category: Dioxole

On April 9, 2007, Gallos, John K.; Stathakis, Christos I.; Salapassidou, Maria J.; Grammatoglou, Constantinos E.; Koumbis, Alexandros E. published an article.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole The title of the article was A short alternative preparation of the bengazoles polyol side-chain segment. And the article contained the following:

A new short and efficient synthesis of the bengazoles side chain I is reported using a sequential diastereoselective Grignard addition, reduction, and regioselective hydroboration on a readily available D-ribose derivative The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to bengazole a synthon polyol isopropylidene hexane tetraol preparation, ribose diastereoselective grignard addition reduction regioselective hydroboration, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Braga, Fernanda Gambogi; Coimbra, Elaine Soares; de Oliveira Matos, Magnum; Carmo, Arturene Maria Lino; Cancio, Marisa Damato; da Silva, Adilson David published an article in 2012, the title of the article was Synthesis and biological evaluation of some 6-substituted purines [Erratum to document cited in CA147:052743].Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole And the article contains the following content:

On page 530, the Abstract contained full citations instead of references numbers; the reference numbers are [11] and [12]. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to erratum purine alkylthio preparation antileishmanial, cytotoxicity leishmania alkylthiopurine derivative erratum, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On January 1, 2014, Stoltz, Kristen L.; Alba, Andrea-Nekane R.; McDonald, Frank E.; Wieliczko, Marika B.; Bacsa, John published an article.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole The title of the article was Iodoetherification of Conformationally Restricted Dienyl Alcohols: Unexpected Formation of Oxocenes by 8-endo-Mode Oxacyclizations. And the article contained the following:

The synthesis of oxocenes I [R = H, (S)-Me, (R)-Me] via iodine-promoted 8-endo-mode oxacyclization from conformationally restricted dienyl alcs. was described. The unsaturated oxocane II was also prepared similarly. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to alkenyl alc preparation iodine oxacyclization, oxocene preparation diastereoselective regioselective, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On April 30, 2007, Braga, Fernanda Gambogi; Coimbra, Elaine Soares; Matos, Magnum de Oliveira; Lino Carmo, Arturene Maria; Cancio, Marisa Damato; da Silva, Adilson David published an article.Application of 38838-06-1 The title of the article was Synthesis and biological evaluation of some 6-substituted purines. And the article contained the following:

We report herein the synthesis and the in vitro antileishmanial evaluation of a series of 6-substituted purines. The most active compounds against Leishmania amazonensis promastigotes were 6-(3′-chloropropylthio)purine [I; R = CH2CH2CH2Cl; (D.A. Benson, I. Karsch-Mizrachi, D.J. Lipman, J. Ostell, B.A. Rapp, D.L. Wheeler, Genbank. Nucleic Acids Res. 28 (2000) 15-18; E.V. Aleksandrova, P.M.I.E. Valashek, J. Med. Pharm. Chem. 35 (2001) 172-173)], 6-(3′-(thioethylamine)propylthio)purine [I; R = CH2CH2CH2SCH2CH2NH2], 6-(α-aceticacidthio)purine [I; R = CH2CO2H] and 6-(6′-deoxy-1′-O-methyl-β-D-ribofuranose)purine [I; R = R’] with an IC50 = 50, 50, 39 and 29 μM, resp. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application of 38838-06-1

The Article related to purine alkylthio preparation antileishmanial, cytotoxicity leishmania alkylthiopurine derivative, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On January 11, 2010, Ghosal, Partha; Kumar, Vikas; Shaw, Arun K. published an article.Category: dioxole The title of the article was A chiron approach to the total synthesis of cytotoxic (+)-muricatacin and (+)-5-epi-muricatacin from D-ribose. And the article contained the following:

A chiron approach strategy toward the total synthesis of (+)-muricatacin [5-[(1S)-1-hydroxytridecyl]-(5S)-2(3H)-dihydrofuranone] and (+)-5-epi-muricatacin starting from com. available and inexpensive D-ribose through the key intermediate (S)-5-((R)-1-hydroxyallyl)furan-2(5H)-one has been disclosed. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Category: dioxole

The Article related to muricatacin total synthesis chiron ribose cross metathesis, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On May 3, 2022, Gao, Yangguang; Deng, Changxuan; Yang, Jie; Lu, Wangting published a patent.Application of 38838-06-1 The title of the patent was Preparation of natural alpha-glucosidase inhibitor Penasulfate A. And the patent contained the following:

The present invention relates to preparation of natural α-glucosidase inhibitor Penasulfate A. In particular, the preparation method comprises of following steps: (1) obtaining compound 6, compound 7 and compound 3 resp.; subjecting compound 6 and 7 to Suzuki coupling reaction to obtain compound 4; the compound 4 and compound 3 are subjected to a first olefin metathesis reaction under the action of a first preset catalyst to obtain compound 16; the compound 16 is further subjected to a first hydrogenation reduction reaction to obtain compound 2 and a methanol solution of acetyl chloride; deprotection reaction of the compound 2 and the methanol solution of acetyl chloride, followed by sulfonylation and pH adjustment, to obtain a natural α-glucosidase inhibitor Penasulfate A that can be produced on a large scale. The inventive method requires only need ten steps, the steps and time required for the reaction are greatly shortened, and the large-scale production of Penasulfate A can be realized. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application of 38838-06-1

The Article related to penasulfate a synthesis alpha glucosidase inhibitor, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On July 17, 2012, Prasad, Kavirayani R.; Revu, Omkar published an article.Quality Control of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole The title of the article was Total synthesis of (+)-cladospolide A. And the article contained the following:

A stereoselective total synthesis of (+)-cladospolide A from D-ribose was described. Key features of the synthesis include olefin cross-metathesis and Yamaguchi lactonization. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Quality Control of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to cladospolide a stereoselective total synthesis, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Quality Control of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On January 31, 1997, Zhu, Bao Hua; Liu, Ze Hua; Yan, Hong; Liu, Jun; Chen, Huilan published an article.Computed Properties of 38838-06-1 The title of the article was The coenzyme B12 analogs-ribosylcobalamins: synthesis, characterization, and photolysis studies. And the article contained the following:

Two analogs of Coenzyme B12, i.e., 1-methyl-5-deoxy-β-D(-)ribofuranos-5-ylcobalamin (RibCbl) and 1-methyl-5-deoxy-2,3-isopropylidene-β-D(-)-ribofuranos-5-yl-cobalamin(RibCbl*), were synthesized. They were characterized by UV-vis and 2D 1H NMR spectroscopies. Furthermore, aerobic and anaerobic photolysis of the two compounds have been studied. Kinetic data of anaerobic photoinduced homolysis for two ribosylcobalamin(AdoCbl) have been determined The half-times under the same exptl. conditions are: RibCbl*, t1/2 = 488 min; RibCbl, t1/2 = 122 min; and AdoCbl, t1/2 = 3 min, resp. Therefore, both of ribosylcobalamins are less photosensitive than Coenzyme B12. These results are discussed in terms of the in-cage chem. process as well as steric and electronic effects of the axial ligand on the Co-C bond homolysis. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Computed Properties of 38838-06-1

The Article related to steric effect bond homolysis methyldeoxyribofuranosylcobalamin preparation, methyldeoxyribofuranosylcobalamin aerobic anaerobic photolysis kinetics, coenzyme b12 analog ribosylcobalamin preparation photolysis and other aspects.Computed Properties of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On June 30, 1996, Blanchard, P.; El Kortbi, M. S.; Fourrey, J.-L.; Lawrence, F.; Robert-Gero, M. published an article.Related Products of 38838-06-1 The title of the article was Relationship between chemical structure and antileishmanial effect of sinefungin analogs. And the article contained the following:

The synthesis of various analogs of sinefungin, e.g. I (R = H, NH2), has been developed by means of an original approach which uses radical chem. The study of their biol. activities revealed that for the antileishmanial effect of sinefungin, the presence of the amino group at C-6′ in the (S)-configuration and the presence of the carboxyl group at C-9′ are necessary. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Related Products of 38838-06-1

The Article related to bactericide antileishmanial nucleoside synthesis, structure activity antileishmanial nucleoside synthesis, nucleoside synthesis antileishmanial effect, sinefungin analog synthesis antileishmanial effect and other aspects.Related Products of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Lerner, Leon M. published an article in 1977, the title of the article was Enantiomeric forms of 9-(5-deoxy-β-erythro-pent-4-enofuranosyl)adenine and a new preparation of 5-deoxy-D-lyxose.Electric Literature of 38838-06-1 And the article contains the following content:

Tosylation of Me 2,3-O-isopropylidene-β-D-ribofuranoside followed by treatment with NaI, deisopropylidenation, benzoylation, and acetolysis gave I. Condensation of I with 6-benzamidochloromercuripurine followed by treatment with 1,5-diazabicyclo[5.4.0]undec-5-ene and subsequent deblocking gave II. The enantiomeric III was similarly prepared from Me 2,3-O-isopropylidene-α-D-lyxopyranoside (IV). Oxidation of Me 2,3-O-isopropylidene-α-D-mannofuranoside with NaIO4 followed by reduction with NaBH4 to give IV and subsequent acid hydrolysis gave D-lyxose. Tosylation of IV followed by reductive cleavage and subsequent hydrolysis gave 5-deoxy-D-lyxose. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Electric Literature of 38838-06-1

The Article related to adenine deoxypentenofuranosyl, pentenofuranosyl deoxy adenine, nucleoside dehydrodeoxy, lyxose deoxy, pentose deoxy, ribofuranose condensation benzamidopurine, purine benzamido condensation ribofuranose and other aspects.Electric Literature of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem