Category: Dioxole

Palladium Nanoparticles-Catalyzed Synthesis of Indanone Derivatives via Intramolecular Reductive Heck Reaction was written by Parveen, Naziya;Sekar, Govindasamy. And the article was included in Advanced Synthesis & Catalysis in 2019.Product Details of 28657-75-2 This article mentions the following:

An efficient protocol for the straightforward, single-step synthesis of 3-aryl-1-indanones I (R¹ = H, 6-Br, 6-Ph, 6-PhCC, 5,6-OCH₂O; R² = Ph, 4-MeOC₆H₄, 3-furyl, 2-indolyl, etc.) from 2′-iodochalcones II via reductive Heck reaction using phosphine free, stable and reusable binaphthyl stabilized palladium nanoparticle (Pd-BNP) as a catalyst is described. An immense array of indanones I using both electron-rich and electron-deficient 2′-iodochalcones was synthesized. Further derivatization of the indanone I (R¹ = H; R² = Ph) was achieved successfully. The heterogeneous nature of the Pd-BNP was validated by centrifugation test and mercury poisoning experiment Pd-BNP was successfully recycled up to 5 cycles without any significant loss in reaction yield and particle size of nanoparticles was confirmed by TEM anal. In the experiment, the researchers used many compounds, for example, 1-(6-Aminobenzo[d][1,3]dioxol-5-yl)ethanone (cas: 28657-75-2Product Details of 28657-75-2).

1-(6-Aminobenzo[d][1,3]dioxol-5-yl)ethanone (cas: 28657-75-2) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Product Details of 28657-75-2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

BF₃·SiO₂-catalyzed one-pot synthesis of α-aminophosphonates in ionic liquid and neat conditions was written by Reddy, Mudumala Veeranarayana;Dindulkar, Someshwar D.;Jeong, Yeon Tae. And the article was included in Tetrahedron Letters in 2011.SDS of cas: 1544-85-0 This article mentions the following:

α-Aminophosphonates were synthesized in a simple and efficient method from the three-component condensation reaction of 5-amino 2,2-difluoro-1,3-benzodioxole, aromatic aldehydes, and di-Et phosphite by silica-supported boron trifluoride (BF₃·SiO₂) in ionic liquid ([bmim][HCl]) under solvent-free conditions at room temperature in good to excellent yields and short reaction times. The catalyst can be recovered and reused for several times without any significant loss of activity. It was observed that a homogeneous reaction medium proved beneficial for the yield of the reaction. In the experiment, the researchers used many compounds, for example, 2,2-Difluorobenzo[d][1,3]dioxol-5-amine (cas: 1544-85-0SDS of cas: 1544-85-0).

2,2-Difluorobenzo[d][1,3]dioxol-5-amine (cas: 1544-85-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.SDS of cas: 1544-85-0

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Nickel-Catalysed Allylboration of Aldehydes was written by Dennis, Francesca M.;Robertson, Craig C.;Partridge, Benjamin M.. And the article was included in Synthesis in 2020.Category: dioxole This article mentions the following:

A nickel catalyst for the allylboration of aldehydes RCHO (R = 4-chlorophenyl, Ph, pyridin-2-yl, cyclohexyl, 2-phenylethane-1-yl, etc.) is reported, facilitating the preparation of anti-homoallylic alcs. RCH(OH)CH(C₆H₅)CH=CH₂ in high diastereoselectivity. The observed diastereoselectivities and NMR experiments suggest that allylation occurs through a well-defined six-membered transition state, with nickel acting as a Lewis acid. In the experiment, the researchers used many compounds, for example, (R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde (cas: 15186-48-8Category: dioxole).

(R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde (cas: 15186-48-8) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Glycidyl Methacrylate Copolymers Modified with CO₂ was written by Yadollahi, M.;Bouhendi, H.;Zohuriaan-Mehr, M. J.;Farhadnejad, H.;Kabiri, K.;Mirabedini, S. M.. And the article was included in Soft Materials in 2013.SDS of cas: 13818-44-5 This article mentions the following:

Functional acrylic resin based on the terpolymer of Bu acrylate (BA)-Me methacrylate (MMA)-glycidyl methacrylate (GMA) was prepared The terpolymer was treated with CO2 gas flow in the presence of cetyltrimethyl ammonium bromide as a catalyst. In terms of the carbonation reaction time, poly(MMA-co-BA-co-GMA-co-2-oxo-1,3-dioxolane-4-yl-Me methacrylate) was prepared in various yields of CO₂ fixation (>90%). Phys., mech., and thermal properties of cured and uncured films were investigated. It was found that, for both cured and uncured films, the mech. properties were improved by increasing carbonation yield. However, their thermal resistance was decreased. In the experiment, the researchers used many compounds, for example, (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate (cas: 13818-44-5SDS of cas: 13818-44-5).

(2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate (cas: 13818-44-5) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.SDS of cas: 13818-44-5

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Analysis of volatile components in Asarum heterotropoides by HS-SPME/GC-MS was written by Wang, Feng;Li, Nan;Li, Xue;Zhong, Lingyan;Huang, Zetian;Hu, Ping. And the article was included in Riyong Huaxue Gongye in 2021.Quality Control of 6-Allyl-4-methoxybenzo[d][1,3]dioxole This article mentions the following:

Asarum is a kind of commonly used traditional Chinese medicine, and volatile oil is the main material basis for its efficacy. In traditional studies, the volatile oil is extracted by steam distillation and analyzed by GC-MS. Although the extraction method is easy to operate and has low cost, it is time-consuming, large sample consumption, high extraction temperature and easy thermal decomposition of active components. Moreover, xylene is often added in this method to promote the stratification of volatile oil, which brings great interference to the subsequent GC-MS anal. and component identification of volatile oil. Therefore, Solid Phase microextraction (SPME) technol. that integrates extraction, purification, enrichment, and sampling functions was used to analyze the volatile oil of Asarum for the first time. The HS-SPME/GC-MS method was established to analyze Asarum heterotropoides, and the volatile components were identified by the NIST spectral library search and retention index. A total of 68 components were identified from the volatile oil of Asarum heterotropoides from 6 origins. The relative content of Me eugenol was the highest among the volatile components with peak area percentages ranging from 17.20% to 33.80%. The application of HS-SPME/GC-MS method to the study of the volatile components in Asarum heterotropoides can reflect the overall differences, and the method is simple and rapid, providing new ideas for the quality evaluation of Asarum heterotropoides. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0Quality Control of 6-Allyl-4-methoxybenzo[d][1,3]dioxole).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Quality Control of 6-Allyl-4-methoxybenzo[d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis and application of nanoporous triple-shelled CuAl₂O₄ hollow sphere catalyst for atmospheric chemical fixation of carbon dioxide was written by Heydari, P.;Hafizi, A.;Rajabzadeh, M.;Karimi, M.;Khalifeh, R.;Rahimpour, M. R.. And the article was included in Journal of the Taiwan Institute of Chemical Engineers in 2020.Recommanded Product: (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate This article mentions the following:

Herein, a copper-alumina spinel hollow sphere with a triple-shell structure developed and applied as a novel catalyst for the cycloaddition of CO₂ at atm. pressure. Different operating conditions such as reaction temperature, various solvents and reaction time were studied in this reaction. Besides, different epoxides were converted into corresponding substituted dioxolanones I [R = CH₂Cl, Ph, CH₂OC₆H₅, etc.] at 80°C, under bubbling of CO₂ at atm. pressure, a catalyst loading of 3 weight% and a reaction time of 24 h with isolated yields up to 100%. In addition, the kinetics of the reaction was investigated at different reaction temperatures by calculating the reaction rate constant and activation energy (based on the Arrhenius equation). The nanoporous triple-shell CuAl₂O₄ hollow microspheres reduce the mass transfer path of different reactant and product mols. along with better accessibility of interior active sites that improved the catalytic efficiency with suitable activity and remarkable cycling stability. In the experiment, the researchers used many compounds, for example, (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate (cas: 13818-44-5Recommanded Product: (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate).

(2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate (cas: 13818-44-5) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Mass spectrometry of the acetal derivatives of selected generally recognized as safe listed aldehydes with ethanol, 1,2-propylene glycol and glycerol was written by Woelfel, Keith;Hartman, Thomas G.. And the article was included in ACS Symposium Series in 1998.Application In Synthesis of 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol This article mentions the following:

The FEMA-GRAS list offers flavor chemists a repertoire of nearly 2000 chems. for use in compounding natural and synthetic flavors for the U.S. marketplace. Aldehydes constitute an important class of these potential flavorants and are widely utilized to impart specific nuances. Alcs. such as ethanol, 1,2-propylene glycol and glycerol are commonly employed as solvents in compounded flavor systems due to their low odor and miscibility in a wide range of aqueous and organic matrixes. However, alcs. and aldehydes react rapidly under anhydrous conditions to form acetal derivatives which often possess different sensory properties. This well known reaction is reversible and its equilibrium is influenced by time, temperature, pH and moisture content. Mass spectra of acetals are currently under represented in com. databases and few literature references are available. Our investigation involved a systematic mass spectrometric study of the acetal derivatives of selected GRAS aldehydes reacted with ethanol, 1,2-propylene glycol and glycerol. Aldehydes from different chem. classes representing saturated and unsaturated aliphatics, aromatics, heterocyclics, terpenoids and others were included for characterization. The corresponding acetals were synthesized, analyzed by GC-MS in electron ionization mode and their retention indexes on a non-polar (polydimethylsiloxane) capillary column were determined A database of mass spectra was produced which includes many previously unreported species. In total, over 60 individual mass spectra were recorded. The characteristic mass spectral fragmentation pathways for each class of acetal are described. In the experiment, the researchers used many compounds, for example, 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol (cas: 68527-74-2Application In Synthesis of 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol).

2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol (cas: 68527-74-2) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Application In Synthesis of 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Convenient syntheses of cyclic carbonates by new reaction of oxiranes with β-butyrolactone was written by Nishikubo, Tadatomi;Iizawa, Takashi;Iida, Makoto;Isobe, Naoki. And the article was included in Tetrahedron Letters in 1986.Name: (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate This article mentions the following:

Cyclic carbonates I [R = CH₂OPh, CH₂OMe, CH₂OBu, CH₂OCH₂CH:CH₂, Ph, CH₂Cl, CH₂O₂CCMe:CH₂] were synthesized by reactions of thes oxiranes II with β-butyrolactone using quaternary salts such as Bu₄NBr as catalyst. In the experiment, the researchers used many compounds, for example, (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate (cas: 13818-44-5Name: (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate).

(2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate (cas: 13818-44-5) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Name: (2-Oxo-1,3-dioxolan-4-yl)methyl methacrylate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

The effect of grafting density and side chain length on the conformation of PEG grafted bottlebrush polymers was written by Xiao, Lifen;Li, Jie;Peng, Gang;Huang, Geng. And the article was included in Reactive & Functional Polymers in 2020.Quality Control of (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol This article mentions the following:

PEG grafted polymers are a kind of promising materials, and widely applied in polymer electrolytes, lubricants, biotechnol. and biomedical science. While up to now, systematical researches of the relationship between architecture and conformation of PEG grafted polymers are very rare. Here, we efficiently and successfully prepared a series of PEG grafted polymers with different grafting d., and side chain length by combining ring-opening metathesis polymerization (ROMP) and Copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, and then characterized the conformations of the synthesized bottlebrush polymers by AFM technique. The AFM images showed that all the polymers P(NB-alkyne)₄₀₀-g-PEG with low grafting d. were spherical morphol., while the polymers P(NB-2alkyne)₄₀₀-g-PEG and P(NB-4alkyne)₃₉₄-g-PEG presented cylindrical morphol., which indicated that only grafting d. could determine the shape of the prepared PNB-g-PEG bottlebrush polymers. While, the side chain length could affect the size of prepared PEG grafted bottlebrush polymers. In the experiment, the researchers used many compounds, for example, (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol (cas: 100-79-8Quality Control of (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol).

(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol (cas: 100-79-8) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Quality Control of (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Easy α-alkylation of ketones with alcohols through a hydrogen autotransfer process catalyzed by RuCl₂(DMSO)₄ was written by Martinez, Ricardo;Ramon, Diego J.;Yus, Miguel. And the article was included in Tetrahedron in 2006.Application of 28657-75-2 This article mentions the following:

The electrophilic α-alkylation of ketones with alcs. is accomplished by a hydrogen autotransfer process catalyzed by RuCl₂(DMSO)₄. The reaction can produce either simple alkylated ketones or α,β-unsaturated ketones just by choosing the appropriate starting ketones (Me ketones or bicyclic methylenic ketones, resp.), as well as quinolines (by using 2-aminobenzyl alc. derivatives) or the corresponding alc. derivatives by the addition of an extra equivalent of the initial alc. In the last case, after the above alkylation process reduction of the carbonyl compound takes place. A mechanistic study seems to indicate that the process goes through the oxidation of the alcs. with ruthenium (after a previous deprotonation) to yield the corresponding aldehyde and a ruthenium hydride intermediate. In turn, the aldehyde suffers a classical aldol reaction with the starting ketone to form the α,β-unsaturated ketone, which finally is reduced through a Michael-type addition by the aforementioned ruthenium hydride intermediate. In the experiment, the researchers used many compounds, for example, 1-(6-Aminobenzo[d][1,3]dioxol-5-yl)ethanone (cas: 28657-75-2Application of 28657-75-2).

1-(6-Aminobenzo[d][1,3]dioxol-5-yl)ethanone (cas: 28657-75-2) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Application of 28657-75-2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem