Category: 1193-11-9

Schurig, V. published the artcileEnantiomer analysis by complexation gas chromatography. Scope, merits and limitations, COA of Formula: C6H12O2, the publication is Journal of Chromatography (1988), 441(1), 135-53, database is CAplus.

The application of complexation gas chromatog. in comtemporary enantiomer anal. was investigated. Enantiomers were separated without derivatization on Chiral metal stationary phases, such as manganese(II), cobalt(II), and nickel(II) bis[3-(heptafluorobutanoyl)-(1R)-camphorate], coated on high-resolution glass and fused-silica open-tubular columns. Enantiomeric excesses (ee) up to 99.9% can be precisely determined by complexation gas chromatog. Employing the gas chromatog.-mass spectrometry (single ion monitoring) technique, the determination of ee and absolute configurations of solutes, present in complex mixtures, can be performed at the low picogram level. For the first time, pertinent sources of error in the gas chromatog. determination of ee were identified and novel exptl. verifications thereof are presented. Interconversion profiles due to inversion of configuration during enantiomer separation by complexation gas chromatog. have been detected. Inconsistencies of an empirical quadrant rule, correlating absolute configuration and order of elution of cyclic ethers from nickel(II) bis[3-(heptafluorobutanoyl)-(1R)-camphorate], are reported.

Journal of Chromatography published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C8H7NO4, COA of Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Salomaa, Pentti published the artcileThe kinetics of the uncatalyzed and acid-catalyzed hydrolysis of 1,3-dioxol-4-one and its derivatives. III. Experiments in moderately concentrated acids and in deuterated solvents, Application of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Acta Chemica Scandinavica (1966), 20(5), 1263-72, database is CAplus.

cf. CA 63, 12995c. The rates of hydrolysis of 1,3-dioxolones (I) containing 0, 1, or 2 Me substituents on the C atom between the 2 ether O atoms, in moderately concentrated HCl and in mixtures of light and heavy water, indicate that the I which have no substituents on the C-2 hydrolyze by the normal type of acid-catalyzed ester hydrolysis. The 2-Me-substituted I are not hydrolyzed by either a normal type or an A-1 type ester hydrolysis. It is suggested that a H₂O mol. is involved in the formation of the critical complex. This idea is supported by experiments in light and heavy water and in their mixtures The gross D solvent-isotope effect (kD/k_H = 1.68) is comparable to that found in the normal type of ester hydrolysis, being lower than in A-1 reactions of acetals and acetal-esters. The behavior in H₂O-D₂O mixtures of different compositions conforms to an equation which is based on 3 exchangeable H atoms in the critical complex. A discussion of the hydrolysis mechanism of 2-Me-substituted I is presented.

Acta Chemica Scandinavica published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Application of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Krzymien, M. E. published the artcileGC-MS analysis of organic vapors emitted from polyurethane foam insulation, Quality Control of 1193-11-9, the publication is International Journal of Environmental Analytical Chemistry (1989), 36(4), 193-207, database is CAplus.

The vapors emitted by rigid polyurethane foam at 40 and 80° in dry and in humid (90% relative humidity) air were trapped with a Tenax TA sampling tube and, after thermal desorption, analyzed by high resolution gas chromatog.-mass spectrometry. The chromatograms demonstrate that the qual. composition of the effluent is basically independent of both temperature and humidity of the foam. Over 70 compounds were identified as polyurethane foam off-gases. Among them the most numerous are hydrocarbons. The most abundant is the blowing agent, CFCl₃. The headspace concentration of the majority of them is <10 mg/m³, there are, however, several compounds with concentration >100 mg/m³.

International Journal of Environmental Analytical Chemistry published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Quality Control of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Kankaanpera, Alpo published the artcileStereochemistry of alkyl-1,3-dioxolanes and the kinetics of their hydrolysis, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Turun Yliopiston Julkaisuja, Sarja A: Physico-Mathematica-Biologica (1966), 68 pp., database is CAplus.

Twenty-three methyl substituted 1,3-dioxolanes (disregarding optical isomers) and 23 other substituted 1,3-dioxolanes were prepared for a kinetic study of their hydrolysis. The structures of 25 isomeric derivatives were deduced from kinetic data and, in some cases, the structures of the reagents used in the synthesis. The equilibrium constants of the interconversion of isomers indicate that the 1,3-dioxolane ring is non planar. The exptl. data can be accounted for if the ring has the shape of the half chair of cyclopentane, and one of the hetero atoms is located on the axis of symmetry. The kinetic data reveal that 1,3-dioxolane and its alkyl derivatives are hydrolyzed by the same mechanism as acyclic acetals. The reactions exhibit a number of special features not observed in previous studies of acetal hydrolysis. Structural factors affecting the rates are: polar effects of substituents which influence the strengths of the bonds broken in the rate determining stage, the eclipsing strain resulting from the interaction of substituents at positions 4 and 5 when the critical complex of the hydrolysis is approached, and steric effects due to the bending of substituents at position 2 toward the 1,3-dioxolane ring.

Turun Yliopiston Julkaisuja, Sarja A: Physico-Mathematica-Biologica published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Daly, James T. published the artcileClosing the loop in the FR community (pulling the same rope instead of pushing it), Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Proceedings of the Annual Conference on Recent Advances in Flame Retardancy of Polymeric Materials (2013), 1-12, database is CAplus.

This paper will address the needs of the com. flame retardant production community, compounders, and our relationships with the FR ingredient manufacturers and the academic FR community. Use of a barrier material with a non-FR-FPUF resulted in the most toxic smoke. The dioxin and furan data indicates that there is not an increase in emission for chlorine containing FR-FPUF.

Proceedings of the Annual Conference on Recent Advances in Flame Retardancy of Polymeric Materials published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Chopade, Shubham P. published the artcileIon-exchange resin-catalyzed ketalization of acetone with 1,4- and 1,2-diols: use of molecular sieve in reactive distillation, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Reactive & Functional Polymers (1999), 42(3), 201-212, database is CAplus.

Ketalization of acetone with 1,4- and 1,2-diols was carried out in the presence of cation exchange resin catalysts to obtain corresponding cyclic ketals viz. dioxepins, dioxepanes and dioxolanes. The reaction is equilibrium controlled and low conversions were achieved in batch mode. Mol. sieves in semi-batch reactive distillation mode were used to remove the H₂O from the reaction mixture This resulted in high conversion of the limiting diol. The batch kinetics was explained by a pseudohomogeneous model. The effects of different configurations as well as various parameters were studied in detail to arrive at optimum conditions. An engineering solution was arrived at to make the process industrially feasible.

Reactive & Functional Polymers published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Zhou, Minghao published the artcileCyclic diethers and short-range solvation: a bifurcated hydrogen-bond model for ether-amine bonding, HPLC of Formula: 1193-11-9, the publication is Journal of Molecular Structure (1992), 187-96, database is CAplus.

Short-range solvation, the effect on solute properties of hydrogen bonding between solute and solvent, has been studied using ethers as the electron-donating solvents, and using the equilibrium constant (K_PT) for the formation of the proton transfer complex between 2,4-dinitrophenol and diethylamine (the proton donor) as a probe. The equilibrium constants (K_SR) for the formation of the solvent-amine hydrogen bond indicate that the tendency for both 5- and 6-membered ring diethers to solvate the amines is 10-20 fold greater than for a noncyclic or cyclic monoether, or a noncyclic diether. It is proposed that the cyclic diether forms a bifurcated hydrogen bond involving both oxygen atoms of the diether. The formation of the short-range solvation structure is affected by substituents on the dioxolane rings in a fashion consistent with the bifurcated bonding model.

Journal of Molecular Structure published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C17H18N2O6, HPLC of Formula: 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Demirel, Zeliha published the artcileAntimicrobial and antioxidant activity of brown algae from the Aegean Sea, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Journal of the Serbian Chemical Society (2009), 74(6), 619-628, database is CAplus.

The present study was conducted to evaluate the antioxidant and anti-microbial activity of methanol, dichloromethane and hexane extracts, as well as the essential oils of brown algae (Phaeophyta) Colpomenia sinuosa, Dictyota dichotoma, Dictyota dichotoma var. implexa, Petalonia fascia and Scytosiphon lomentaria. The essential oil of the macroalgae was obtained by steam distillation and analyzed by GC and GC/MS. The antioxidant activity of the algal extracts was determined using the procedures of inhibition of β-carotene bleaching and ABTS⁺ methods. The antioxidant effects of the extracts were compared with those of com. antioxidants, such as butylated hydroxytoluene (BHT), butylated hydroxyanisol (BHA) and α-tocopherol. The hexane extracts of D. dichofoma var. implexa had a higher phenolic content than the other extracts The dichloromethane extract of S. lomentaria was found to be more active in the decolorization of ABTS⁺ than the other extracts and generally the dichloromethane extracts were more active than the methanol and hexane extracts Antimicrobial activities of the extracts were assessed against Gram (+) and Gram (-) bacteria and one yeast strain by the disk diffusion method. According to the results, the dichloromethane extracts generally showed more potent antimicrobial activity than the methanol and hexane extracts at concentrations 1.5 and 1.0 mg/disk.

Journal of the Serbian Chemical Society published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Koz, F. Ferda Yilmaz published the artcileAntioxidant and antimicrobial activities of Codium fragile (Suringar) Hariot (Chlorophyta) essential oil and extracts, HPLC of Formula: 1193-11-9, the publication is Asian Journal of Chemistry (2009), 21(2), 1197-1209, database is CAplus.

Macroalgae are rich sources of natural bioactive products. Their secondary metabolites are attracted attends in many fields of life i.e., food, animal feeding, textile, cosmetics, medicine etc. In this study, methanol, dichloromethane and hexane extracts of Codium fragile (Chlorophyta) were tested for antimicrobial and antioxidant activities. Antioxidant effects were evaluated by hydroxyl radical scavenging assay (deoxyribose degradation assay) and β-carotene bleaching assay. The extracts indicated relatively little antioxidant activities, as compared to com. antioxidants. The composition of the essential oil of C. fragile was also analyzed by GC and GC-MS. Twenty four compounds were identified of C. fragile essential oil and n-tricosane (11.88 %) was determined as major component. Essential oil of C. fragile showed weak antibacterial activity against all gram pos. bacteria tested, except methicillin-oxacillin resistant Staphylococcus aureus ATCC 43300. Similarly, all the extracts of C. fragile showed weak antimicrobial activity on tested organisms.

Asian Journal of Chemistry published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, HPLC of Formula: 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Yamada, Kenichi published the artcileIntroduction of Functionalized C1, C2, and C3 Units to Imines through the Dimethylzinc-Air-Initiated Radical Addition, Safety of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Journal of Organic Chemistry (2004), 69(5), 1531-1534, database is CAplus and MEDLINE.

Introduction of functionalized C1, C2, and C3 units to imines was achieved by using the dimethylzinc-air-initiated α-alkoxyalkyl radical addition as a key reaction. The addition to a C:N double bond chemoselectively occurred in the presence of a C:O double bond, which is one of the advantages of this radical addition reaction over ionic addition reactions. The dimethylzinc-mediated reaction of 4-methyl-N-(phenylmethylene)benzenesulfonamide (I) with 2,2-dimethyl-1,3-dioxolane gave rel-N-[(R)-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl](phenyl)methyl]-4-methylbenzenesulfonamide (II) as the major product. Hydrolysis of II gave rel-N-[(2R,3R)-2,3-dihydroxy-1-phenylpropyl]-4-methylbenzenesulfonamide (III).

Journal of Organic Chemistry published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C12H14S, Safety of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem