In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Cu-Catalyzed site-selective C(sp2)-H radical trifluoromethylation of tryptophan-containing peptides, published in 2020-03-06, which mentions a compound: 7524-52-9, mainly applied to tryptophan peptide radical trifluoromethylation copper catalyst chirality; crystal structure tryptophan trifluoromethylation reaction mechanism solvent effect, Name: H-Trp-OMe.HCl.
Site-selective functionalization of C-H bonds within a peptide framework poses a challenging task of paramount synthetic relevance. Herein, we report an operationally simple C(sp2)-H trifluoromethylation of tryptophan (Trp)-containing peptides. This fluorination technique is characterized by its chirality preservation, tolerance of functional groups, and scalability and exhibits chemoselectivity for Trp residues over other amino acid and heterocyclic units. As a result, it represents a sustainable tool toward the late-stage peptide modification and protein engineering.
Here is a brief introduction to this compound(7524-52-9)Name: H-Trp-OMe.HCl, if you want to know about other compounds related to this compound(7524-52-9), you can read my other articles.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem