Alaimo, Robert J.; Pelosi, Stanford S.; Hatton, Christopher J.; Gray, Joseph E. published the article 《Antiparasitic thiocyanatobenzothiazoles》. Keywords: anthelmintic fungicide thiocyanatobenzothiazole; benzothiazole thiocyanato yeast antiparasitic.They researched the compound: 6,7-Dichlorobenzo[d]thiazol-2-amine( cas:25150-27-0 ).Reference of 6,7-Dichlorobenzo[d]thiazol-2-amine. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:25150-27-0) here.
A series of 7 title compound was prepared by the reaction of the appropriate aniline derivative with thiocyanogen [505-14-6] generated in situ followed by thermal cyclization. The activity of 2-amino-6-ethyl-4-thiocyanatobenzothiazole (I) [37069-20-8] against Ascaris suum and Hymenolepis nana in mice was comparable to that of dl-tetramisole [5036-02-2] and bunamidine [3748-77-4], resp. 2-Amino-7-chloro-6-fluoro-4-thiocyanatobenzothiazole (II) [37525-33-0] and 2-amino-6,7-dichloro-4-thiocyanatobenzothiazole (III) [37069-18-4] were active in vitro against several yeast species, including Candida albicans and Microsporum canis.
After consulting a lot of data, we found that this compound(25150-27-0)Reference of 6,7-Dichlorobenzo[d]thiazol-2-amine can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem