Application In Synthesis of 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine, is researched, Molecular C34H22NO2P, CAS is 1265884-98-7, about Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes. Author is Sandmeier, Tobias; Krautwald, Simon; Zipfel, Hannes F.; Carreira, Erick M..
Fully stereodivergent dual-catalytic α-allylation of protected α-amino- and α-hydroxyacetaldehydes is achieved through iridium- and amine-catalyzed substitution of racemic allylic alcs. with chiral enamines generated in situ. The operationally simple method furnishes useful aldehyde building blocks in good yields, more than 99 % ee, and with d.r. values greater than 20:1 in some cases [e.g., allylation of 2-phthalimidoacetaldehyde with Ph vinyl carbinol in presence of [Ir(cod)Cl]2 complex with (R)-I/(S)-II in presence of dichloroacetic acid afforded (R,R)-III (81% yield, >99% ee, >20:1 d.r.)]. Addnl., the γ,δ-unsaturated products can be further functionalized in a stereodivergent fashion with high selectivity and with preservation of stereochem. integrity at the Cα position.
After consulting a lot of data, we found that this compound(1265884-98-7)Application In Synthesis of 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem