Berhal, Farouk published the artcileRh-catalyzed asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated ketones with DIFLUORPHOS and SYNPHOS analogues, Computed Properties of 503538-69-0, the publication is Journal of Organic Chemistry (2011), 76(15), 6320-6326, database is CAplus and MEDLINE.
Applications of electron-deficient DIFLUORPHOS and SYNPHOS analogs in the rhodium-catalyzed asym. conjugate addition of boronic acids to α,β-unsaturated ketones afford the 1,4-addition adducts e. g., I and II in yields up to 92% and with 99% ee. Particularly, a Rh-catalyzed asym. 1,4-addition of arylboronic acids to nonsubstituted maleimide substrates using the (R)-3,5-diCF3-SYNPHOS ligand is also reported. This protocol provides access to various enantioenriched 3-substituted succinimide units of biol. interest, in high yields and good to excellent ee up to 93%, which could be upgraded up to 99% ee, after a single crystallization
Journal of Organic Chemistry published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Computed Properties of 503538-69-0.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem