Anteunis, M. published the artcileNuclear magnetic resonance experiments on ketals. III. Proton magnetic resonance (P.M.R.) spectrum and conformations of the glycol ketal of 1,2-propanediol with acetone and acetaldehyde, Safety of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Bulletin des Societes Chimiques Belges (1964), 73(11-12), 889-97, database is CAplus.
cf. CA 61, 10570h. The H N.M.R. (P.M.R.) spectra of 2,2,4-trimethyl-1,3-dioxolane (I) and cis- and trans-2,4-dimethyl-1,3-dioxolane (II) were determined and analyzed. The chem. shifts are in accordance with a half-chair conformation. The 1,3-H-Me interaction causes an upfield shift of ∼0.15 ppm. when the 2 are cis to one another. A similar shift of 0.05 ppm. was noted for a cis-1,3-Me-Me interaction. In I and cis-II, long-range coupling between the 4-Me and the methylene H cis to it is observed. I (b. 100°) was prepared from Me2C(OMe)2 (0.3 moles), propanediol (III) (0.2 moles), and H2SO4 catalyst. II was prepared by slow distillation of MeCH0 from acidified paraldehyde into III. Separation of the product by gas-liquid chromatography gave cis-II, b. 91.8°, n25 1.3945, d23.6 0.92786, m. 55-60°; and trans-II, b. 89.5°, n25 1.3928; d23.0 0.91570. meso4,5-Dimethyl-1,3-dioxolane (b. 104°) was prepared by azeotropic H2O removal with C6H6 from a mixture of monobutanediol and (HCHO)x. The HCHO ketal of 4,5-trimethylene-1,3-dioxolane prepared similarly b. 80°/18 mm.
Bulletin des Societes Chimiques Belges published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Safety of 2,2,4-Trimethyl-1,3-dioxolane.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem