On December 31, 2016, Ajay, Sama; Arora, Inderpreet; Saidhareddy, Puli; Shaw, Arun K. published an article.COA of Formula: C9H15IO4 The title of the article was Diversity-Oriented Synthesis of cis-3,4-Dihydroxylated Piperidine and Its Higher Saturated and Unsaturated Homologues from D-Ribose and Their Glycosidase-Inhibition Study. And the article contained the following:
The synthesis of six-, seven-, and eight-membered cis-dihydroxy azacycles has been accomplished from D-ribose using Vasella reductive amination as a key step and utilization of hydroboration-oxidation, Mitsunobu reaction, and ring-closing metathesis (RCM) reactions in a facile manner. These homologous dihydroxylated heterocyclic scaffolds were subjected to the glycosidase inhibition assays. However, only a moderate inhibitory activity for three out of five compounds was observed against α-glucosidases with a high degree of selectivity. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).COA of Formula: C9H15IO4
The Article related to cis dihydroxy azacycle preparation glycosidase inhibitor, ribose reductive amination hydroboration oxidation mitsunobu ring closing metathesis, Heterocyclic Compounds (One Hetero Atom): Higher-Membered Rings and other aspects.COA of Formula: C9H15IO4
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem