New discoveries in chemical research and development in 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 18422-53-2, Name is 1,2:4,5-Di-O-Isopropylidene-Beta-D-Erythro-2,3-Hexodiulo-2,6-Pyranose, molecular formula is C12H18O6. In an article, author is Trachsel, D,once mentioned of 18422-53-2, HPLC of Formula: C12H18O6.
Synthesis of fluoro analogues of 3,4-(methylenedioxy)amphetamine (MDA) and its derivatives
The role of the metabolism of the entactogen 3,4-(methylenedioxy)methamphetamine (MDMA 1b) in neurotoxic or psychopharmacologic action is widely discussed, but not yet fully understood. To prompt further investigation into the role of MDMA metabolism, six new 3,4-(difluoromethylenedioxy) analogues of MDMA (1b) were prepared and characterized. Although electronically very different, the fluoro analogues 3-5 should be sterically very similar to the non-fluorinated parent compounds. The Fatoms may prevent the formation of toxic metabolites produced via a radical pathway (Scheme 1). Different theories regarding MDMA-induced neurotoxicity are briefly reviewed and discussed. The novel compounds 3-5 may help to verify the hypothesis that MDMA-induced neurotoxicity is the result of the formation of metabolites lacking the methylenedioxy bridge.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 18422-53-2 help many people in the next few years. HPLC of Formula: C12H18O6.
Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem