Concise formation of spirocyclic compounds for marine phycotoxins was written by Ishihara, Jun;Tojo, Shingo;Makino, Takuya;Sekiya, Hiroshi;Tanabe, Akiko;Shiraishi, Mitsutaka;Murai, Akio;Hatakeyama, Susumi. And the article was included in Heterocycles in 2017.Recommanded Product: 15186-48-8 This article mentions the following:
The stereoselective construction of azaspiro[5.6]dodecenone skeletons, e.g. I by the chiral BOX/copper-mediated Diels-Alder reaction was described. The cycloaddition reaction of α-methylene caprolactams and functionalized dienes allowed the concise formation of spirocyclic structures of marine phycotoxins, such as pinnatoxin and spirolide. In the experiment, the researchers used many compounds, for example, (R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde (cas: 15186-48-8Recommanded Product: 15186-48-8).
(R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde (cas: 15186-48-8) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: 15186-48-8
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem