Deng, Lan published the artcileA novel synthesis method of baicalein derivatives and their bronchodilation activity, SDS of cas: 110204-45-0, the publication is Zhongguo Yaoke Daxue Xuebao (2010), 41(5), 414-418, database is CAplus.
Ten baicalein derivatives with bronchodilation activity were selectively synthesized using baicalin as a starting material and applying its glucosyl group as a protecting group. Their structures were confirmed by IR, MS, and 1H NMR data. The preliminary biol. assay results showed that the baicalein derivatives could inhibit contraction of tracheal smooth muscle induced by acetylcholine (Ach), KCl, and histamine (His) in guinea pig. This finding indicates a potential application of baicalein derivatives in chronic obstructive pulmonary diseases (COPD).
Zhongguo Yaoke Daxue Xuebao published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, SDS of cas: 110204-45-0.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem