Bonilla-Landa, Israel’s team published research in Current Organic Synthesis in 16 | CAS: 177-10-6

Current Organic Synthesis published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Category: dioxole.

Bonilla-Landa, Israel published the artcileHafnium(IV) Chloride Catalyzes Highly Efficient Acetalization of Carbonyl Compounds, Category: dioxole, the publication is Current Organic Synthesis (2019), 16(6), 913-920, database is CAplus and MEDLINE.

Hafnium(IV) tetrachloride efficiently catalyzes the protection of a variety of aldehydes and ketones RC(O)R1 (R = Ph, 4-butylphenyl, pyridin-2-yl, octyl, etc.; R1 = H, Me, Et), including benzophenone, acetophenone, and cyclohexanone, to the corresponding di-Me acetals and 1,3-dioxolanes, RC(OR2)2R1 (R2 = Me, -(CH2)2-) under microwave heating. Substrates possessing acid-labile protecting groups (TBDPS and Boc) chemoselectively generated the corresponding acetal/ketal in excellent yields.

Current Organic Synthesis published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem