Acetalization of ethyl acetoacetate with glycol over silica gel supported phosphotungstic acid catalyst was written by Yu, Qingyue;Zhou, Zhiwei;Wu, Wenliang;Yun, Zhi. And the article was included in Huaxue Fanying Gongcheng Yu Gongyi in 2009.Application In Synthesis of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate The following contents are mentioned in the article:
A series catalysts of phosphotungstic acid (PW) supported on silica gel were prepared by sol-gel method and characterized by means of X-ray diffraction (XRD), low temperature adsorption and desorption of N2, and temperature-programmed desorption of ammonia (NH3-TPD). The catalytic performance was determined by acetalization of Et acetoacetate with glycol. The results showed that when the loading mass fraction of PW was 40%, PW was highly dispersed on silica gel, the pores were regular, the surface area was 187 m2/g and the acid amount was high, and the conversion of Et acetoacetate and the selectivity of fructone were 96.8% and 98.5%, resp., under the conditions of the molar ratio of Et acetoacetate to glycol 1:1.3, reaction temperature 353 K and reaction time 30 min. The stability tests showed that the conversion of Et acetoacetate and the selectivity of fructone were 93.1% and 98.0%, resp., after the catalyst was used 15 times. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Application In Synthesis of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate).
Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Application In Synthesis of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem