Kosarac, Ivana published the artcileOpen characterization of vaping liquids in canada: chemical profiles and trends, Quality Control of 68527-74-2, the publication is Frontiers in Chemistry (Lausanne, Switzerland) (2021), 756718, database is CAplus and MEDLINE.
Currently, there is a lack of comprehensive data on the diversity of chems. present in vaping liquids To address this gap, a non-targeted anal. of 825 vaping liquids collected between 2017 and 2019 from Canadian retailers was conducted. Prior to mass spectrometry anal., samples were diluted 1:500 volume/volume with methanol or acetonitrile. Chem. compound separation and anal. was carried out using gas chromatog. and triple quadrupole mass spectrometry (GC-MS/MS) systems operated in the full scan mode and mass range of 35-450 m/z. Mass spectrum for each sample was obtained in electron ionization at 70 eV and processed. Non-targeted identification workflow included use of automated mass spectral deconvolution and identification system (AMDIS), where required, as well as a number of com. available spectral libraries. In order to validate identities, an inhouse database of expected compounds previously detected in vaping liquids was used along with genuine anal. standards for compounds of interest. This resulted in a dataset of over 1,500 unique detected chems. Approx. half of these chem. compounds were detected only once in a single product and not in multiple products analyzed. For any sample analyzed, on average, 40% of the chem. constituents appeared to have flavoring properties. The remainder were nicotine and related alkaloids, processing, degradation or indirect additives, natural extractives and compounds with unknown roles. Data published here from the project on the Open Characterization of vaping liquids is unique as it offers a detailed understanding of products’ flavor chem. profiles, the presence and frequency of chems. of potential health concern, as well as trends and changes in products’ chem. complexity over a three-year period. Non-targeted chem. surveillance such as this present valuable tools to public health officials and researchers in responding to emergent issues such as vaping associated lung injury or informing chem. based strategies which may be aimed at addressing product safety or appeal.
Frontiers in Chemistry (Lausanne, Switzerland) published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, Quality Control of 68527-74-2.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem