Cai, Xian-Feng published the artcileSynthesis of chiral exocyclic amines by asymmetric hydrogenation of aromatic quinolin-3-amines, Application of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Chemistry – A European Journal (2014), 20(24), 7245-7248, database is CAplus and MEDLINE.
Asym. hydrogenation of aromatic quinolin-3-amines was successfully developed with up to 94 % enantiomeric excess (ee). Introduction of the phthaloyl moiety to the amino group is crucial to eliminate the inhibition effect caused by the substrate and product, to activate the aromatic ring, and to improve the diastereoselectivity. This new methodol. provides direct and facile access to chiral exocyclic amines. Notably, this report is the first on the highly enantioselective hydrogenation of aromatic amines. The structures and absolute configuration of the compounds were confirmed by the single crystal x-ray diffraction anal. of 4-methyl-N-((2S,3S)-2-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide and its crystallog. data were deposited at the Cambridge Crystallog. Data Center as supplementary publication number CCDC 962689.
Chemistry – A European Journal published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Application of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem