Rigo, Davide’s team published research in ACS Sustainable Chemistry & Engineering in 7 | CAS: 1193-11-9

ACS Sustainable Chemistry & Engineering published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Rigo, Davide published the artcileAcid-Catalyzed Reactions of Isopropenyl Esters and Renewable Diols: A 100% Carbon Efficient Transesterification/Acetalization Tandem Sequence, from Batch to Continuous Flow, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is ACS Sustainable Chemistry & Engineering (2019), 7(23), 18810-18818, database is CAplus.

A new acid-catalyzed tandem sequence was investigated for the upgrading of renewable 1,2-diols such as propylene glycol (PG) and ethylene glycol (EG), with isopropenyl esters. For example, at 50 °C and in the presence of Amberlyst-15, the reaction of PG with nontoxic isopropenyl acetate allowed an initial irreversible monotransesterification of the diol, releasing acetone which then promoted acetalization on a second mol. of the glycol. The overall protocol was 100% carbon efficient, affording water as the sole byproduct. The reaction scope was extended to higher homologs of enol esters as isopropenyl-octanoate and phenylbutyrate. Addnl., the tandem sequence was successfully transferred in the continuous-flow (CF) mode where the catalyst (Amberlyst-15) could be used virtually indefinitely without loss of performance, and the solvent (THF or CPME) was quant. recovered and reused. Under CF conditions, the reaction of PG with isopropenyl acetate could be run at 30 °C and atm. pressure with a (nonoptimized) productivity up to 9.7 mmol gcat-1 h-1, 3 times higher than that achieved in the batch mode. When ethylene glycol was used, a lower tandem selectivity was observed due to predominance of transesterification products, mono- and diesters, over the acetal compound A 100% carbon efficient upgrading of renewable 1,2-diols through tandem monotransesterification and acetalization reactions mediated by isopropenyl esters is presented.

ACS Sustainable Chemistry & Engineering published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem