Flores, Rosa M. published the artcileEvaluation of multistep derivatization methods for identification and quantification of oxygenated species in organic aerosol, Product Details of C6H12O2, the publication is Journal of Chromatography A (2015), 1-11, database is CAplus and MEDLINE.
Two, 3-step methods to derivatize mono- and multi-functional species with carbonyl (C=O), carboxylic acid (-COOH), and alc. (-OH) moieties were compared and optimized. In Method 1, C=O, -COOH, and -OH moieties were converted to methyloximes (R-C=N-OCH3) with O-methylhydroxylamine hydrochloride (MHA); to Me esters (O=C-R-OCH3) with (trimethylsilyl)diazomethane in methanol (TMSD/MeOH); and to trimethylsilyl ethers [R-OSi(CH3)3] with N,O-bis(trimethylsilyl)-trifluoroacetamide (BSTFA) containing 1% trimethylchlorosilane, resp. Steps 1 and 3 of methods were identical; however, in Step 2 of Method 2, -COOH moieties were derivatized with 10% (volume/volume) BF3 in MeOH or n-butanol (n-BuOH). The BF3/MeOH and BF3/n-BuOH were ineffective at converting species with >2-OH moieties. Average standard deviations for derivatization of 36 model compounds by the 3-step methods using TMSD/MeOH and BF3/MeOH were 7.4 and 14.8%, resp. Average derivatization efficiencies for Methods 1 and 2 were 88.0 and 114%, resp. Despite the lower average derivatization efficiency of Method 1, distinct advantages included a greater certainty of derivatization yield for the entire suite of mono- and multi-functional species and fewer processing steps for sequential derivatization. Detection limits for Method 1 using multi-dimensional gas chromatog./time of flight mass spectrometry (GC × GC-ToF-MS) were 0.3-54 pg/m3. Approx. 100 oxygenated organic species were identified and quantified in aerosols filtered from 39 m3 air in an urban location. Levels of species were 0.013-17 ng/m3 and were nearly all above Method 1 limits of detection.
Journal of Chromatography A published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Product Details of C6H12O2.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem