The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine( cas:1265884-98-7 ) is researched.Related Products of 1265884-98-7.Han, Min; Yang, Min; Wu, Rui; Li, Yang; Jia, Tao; Gao, Yuanji; Ni, Hai-Liang; Hu, Ping; Wang, Bi-Qin; Cao, Peng published the article 《Highly Enantioselective Iridium-Catalyzed Coupling Reaction of Vinyl Azides and Racemic Allylic Carbonates》 about this compound( cas:1265884-98-7 ) in Journal of the American Chemical Society. Keywords: enantioselective iridium catalyst coupling reaction vinyl azide allylic carbonate; amide nitrile stereoselective preparation. Let’s learn more about this compound (cas:1265884-98-7).
The iridium-catalyzed enantioselective coupling reaction of vinyl azides and allylic electrophiles is presented and provides access to β-chiral carbonyl derivatives Vinyl azides are used as acetamide enolate or acetonitrile carbanion surrogates, leading to γ,δ-unsaturated β-substituted amides as well as nitriles with excellent enantiomeric excess. These products are readily transformed into chiral N-containing building blocks and pharmaceuticals. A mechanism is proposed to rationalize the chemoselectivity of this coupling reaction.
Although many compounds look similar to this compound(1265884-98-7)Related Products of 1265884-98-7, numerous studies have shown that this compound(SMILES:N1(P2OC3=CC=C4C=CC=CC4=C3C5=C6C=CC=CC6=CC=C5O2)C7=CC=CC=C7C=CC8=CC=CC=C81), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem