So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Wang, Zhen; Zhang, Ling; Zhang, Fugeng; Wang, Bin researched the compound: H-Trp-OMe.HCl( cas:7524-52-9 ).Safety of H-Trp-OMe.HCl.They published the article 《Synthesis of β-carbolines through tetra-n-butylammonium bromide mediated cycloaromatization reaction of N-methylaniline with tryptophan derivatives》 about this compound( cas:7524-52-9 ) in Youji Huaxue. Keywords: beta carboline preparation; tryptophan ester methylaniline cycloaromatization tetrabutylammonium bromide. We’ll tell you more about this compound (cas:7524-52-9).
A mild and efficient nBu4NBr-mediated oxidative cycloaromatization to prepare β-carbolines from readily available tryptophans and N-methylaniline is described. The present metal free protocol is complementary to the existing methods for the synthesis of aromatic β-carbolines.
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Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem