Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Organic Letters called C-H olefination of tryptophan residues in peptides: Control of residue selectivity and peptide-amino acid cross-linking, Author is Terrey, Myles J.; Holmes, Ashley; Perry, Carole C.; Cross, Warren B., which mentions a compound: 7524-52-9, SMILESS is N[C@@H](CC1=CNC2=CC=CC=C12)C(OC)=O.[H]Cl, Molecular C12H15ClN2O2, Product Details of 7524-52-9.
There is high demand for new methods to modify peptides, for application in drug discovery and biomedicine. A C-H functionalization protocol for the olefination of tryptophan residues in peptides is described. The modification is successful for Trp residues at any position in the peptide, has broad scope in the styrene coupling partner, and offers opportunities for conjugating peptides with other biomols. For peptides containing both Trp and Phe, directing group manipulation enables full control of residue selectivity.
Here is just a brief introduction to this compound(7524-52-9)Product Details of 7524-52-9, more information about the compound(H-Trp-OMe.HCl) is in the article, you can click the link below.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem