Name: 2-Bromomethyl-1,3-dioxolane. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 2-Bromomethyl-1,3-dioxolane, is researched, Molecular C4H7BrO2, CAS is 4360-63-8, about Design, synthesis, and biological evaluation of novel 6H-benzo[c]chromen-6-one derivatives as potential phosphodiesterase II inhibitors. Author is Tang, Long; Jiang, Jianchun; Song, Guoqiang; Wang, Yajing; Zhuang, Ziheng; Tan, Ying; Xia, Yan; Huang, Xianfeng; Feng, Xiaoqing.
Urolithins (hydroxylated 6H-benzo[c]chromen-6-ones) were the main bioavailable metabolites of ellagic acid (EA), which was shown to be a cognitive enhancer in the treatment of neurodegenerative diseases. A series of alkoxylated 6H-benzo[c]chromen-6-one derivatives I [R = H, OMe; R1 = Me, Et, Bn, etc.] via reaction of hydroxy-benzo[c]chromenones and alkyl halides were designed and synthesized. Furthermore, their biol. activities were evaluated as potential PDE2 inhibitors, and the alkoxylated 6H-benzo[c]chromen-6-one derivative I [R = H, R1 = n-Bu] was found to have the optimal inhibitory potential (IC50: 3.67 ± 0.47μM). Compound 6H-benzo[c]chromen-6-one derivative I [R = H, R1 = n-Bu] also exhibited comparable activity in comparison to that of BAY 60-7550 in vitro cell level studies.
From this literature《Design, synthesis, and biological evaluation of novel 6H-benzo[c]chromen-6-one derivatives as potential phosphodiesterase II inhibitors》,we know some information about this compound(4360-63-8)Name: 2-Bromomethyl-1,3-dioxolane, but this is not all information, there are many literatures related to this compound(4360-63-8).
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem