The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Bromomethyl-1,3-dioxolane( cas:4360-63-8 ) is researched.Recommanded Product: 2-Bromomethyl-1,3-dioxolane.Nedolya, N. A.; Tarasova, O. A.; Albanov, A. I.; Trofimov, B. A. published the article 《Synthesis and Unexpected Transformation of 5-[(1,3-Dioxolan-2-ylmethyl)sulfanyl]-1H-pyrrol-2-amine into 5-{[2-(2-Hydroxyethoxy)ethenyl]sulfanyl}-1H-pyrrol-2-amine in the Presence of a Superbase》 about this compound( cas:4360-63-8 ) in Russian Journal of Organic Chemistry. Keywords: ethenyloxyethyl diethyl hydroxyethoxy ethenylsulfanyl pyrrolamine preparation diastereoselective; dioxolanylmethylsulfanyl ethenyloxyethyl diethylpyrrolamine preparation one pot transformation potassium butoxide; diethylpropynamine ethenyloxyethyl isothiocyanate bromomethyl dioxolane cyclization potassium butoxide. Let’s learn more about this compound (cas:4360-63-8).
Successive one-pot reactions of monolithiated N,N-diethylprop-2-yn-1-amine with 2-(ethenyloxy)ethyl isothiocyanate and 2-(bromomethyl)-1,3-dioxolane afforded I in 91% yield. In the system t-BuOK-DMSO at room temperature (1 h), the product was converted to E/Z-II (yield 68%) instead of expected 1-vinyl derivative
There is still a lot of research devoted to this compound(SMILES：BrCC1OCCO1)Recommanded Product: 2-Bromomethyl-1,3-dioxolane, and with the development of science, more effects of this compound(4360-63-8) can be discovered.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem