Quality Control of H-Trp-OMe.HCl. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: H-Trp-OMe.HCl, is researched, Molecular C12H15ClN2O2, CAS is 7524-52-9, about Incorporation of the pentafluorosulfanyl group through common synthetic transformations. Author is Hiscocks, Hugh G.; Yit, Dylan Lee; Pascali, Giancarlo; Ung, Alison T..
The incorporation of SF5 group into model amino acids has been achieved using com. available synthons substituted with this group. This work investigates the influence of the -SF5 group on a variety of common synthetic transformations utilized in fields of bioconjugation and drug development, namely, amide coupling, reductive amination, diazo-coupling, and CuAAC “”Click”” reactions. The influence of the novel substituent on the success of these common transformations is presented, and alternative approaches for those which proved unsatisfactory are proposed herein.
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Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem