The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: H-Trp-OMe.HCl( cas:7524-52-9 ) is researched.Computed Properties of C12H15ClN2O2.Brandhofer, Tobias; Stinglhamer, Martin; Derdau, Volker; Mendez, Maria; Poverlein, Christoph; Garcia Mancheno, Olga published the article 《Easy access to drug building-blocks through benzylic C-H functionalization of phenolic ethers by photoredox catalysis》 about this compound( cas:7524-52-9 ) in Chemical Communications (Cambridge, United Kingdom). Keywords: tyrosine methyl ester functionalization alkylation methyl acrylate photoredox catalysis; peptide synthesis alkylation photoredox catalysis reaction mechanism cyclic voltammetry. Let’s learn more about this compound (cas:7524-52-9).
A visible light-mediated photocatalyzed C-C-bond forming method for the benzylic C-H functionalization of phenolether containing synthetic building blocks based on a radical-cation/deprotonation strategy is reported. This method allows the mild, selective generation of benzyl radicals in phenolic complex mols. and drug-like compounds, providing new entries in synthetic and medicinal chem.
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Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem