Month: December 2022

Photocatalytic activation of alkyl chlorides by assembly-promoted single electron transfer in microheterogeneous solutions was written by Giedyk, Maciej;Narobe, Rok;Weiss, Sophia;Touraud, Didier;Kunz, Werner;Koenig, Burkhard. And the article was included in Nature Catalysis in 2020.Formula: C7H13ClO2 This article mentions the following:

Photoredox catalysis has developed into a powerful tool for the synthesis of organic compounds with diverse structures. However, stable carbon-chloride bonds remain beyond the energetic limits of the outer-sphere photoreductive activation. Herein, the organization of the reacting species in microstructured, aqueous solutions is demonstrated which allows generation of carbon-centered radicals from non-activated alkyl chlorides in the presence of double bonds via assembly-promoted single electron transfer. Photocatalytic systems consisting of a surfactant, organic substrates and additives have been designed, characterized and applied for radical dechlorination, addition and cyclization reactions. Cheap and com. available blue light-emitting diodes are used as the irradiation source for the transformations. Mechanistic studies indicate the accumulation of the energy of two visible light photons in one catalytic cycle. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Formula: C7H13ClO2).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Formula: C7H13ClO2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Lithiated anions derived from (alkenyl)pentamethyl phosphoric triamides: Useful synthons for the stereoselective synthesis of 9-oxo- and 10-hydroxy-2(E)-decenoic acids, important components of queen substance and royal jelly of honeybee Apis mellifera was written by Olszewski, Tomasz K.;Bomont, Catherine;Coutrot, Philippe;Grison, Claude. And the article was included in Journal of Organometallic Chemistry in 2010.Reference of 118336-86-0 This article mentions the following:

Lithiated anions derived from (alkenyl)pentamethyl phosphoric triamides as homoenolate equivalent are used in the reaction with halogenated acetal and ketal giving regioselectively the γ-alkylation adducts. Chemoselective acidic hydrolysis of the enephosphoramide moiety in the presence of acetal or ketal groups leads to expected carbonyl products, key intermediates in the synthesis of natural compounds The synthetic potential of the presented strategy is illustrated by stereoselective synthesis of two pheromones namely, 9-oxo-2(E)-decenoic acid from queen substance and 10-hydroxy-2(E)-decenoic acid from royal jelly of honeybee Apis mellifera. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Reference of 118336-86-0).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Reference of 118336-86-0

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

A new method for bromination: use of tetrabutylammonium tribromide was written by Fournier, M.;Fournier, F.;Berthelot, J.. And the article was included in Bulletin des Societes Chimiques Belges in 1984.Application of 3418-21-1 This article mentions the following:

Styrenes and ketones were treated with Bu₄N⁺ Br₃^– to give the resp. dibromo derivatives and α-bromo ketones. Thus, PhCH:CH₂ was treated with Bu₄N⁺ Br₃^– to give PhCHBrCH₂Br₂. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Application of 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Application of 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis of novel 5-aryl-2-thio-1,3,4-oxadiazoles and the study of their structure-antimycobacterial activities was written by Macaev, Fliur;Rusu, Ghenadie;Pogrebnoi, Serghei;Gudima, Alexandru;Stingaci, Eugenia;Vlad, Ludmila;Shvets, Nathaly;Kandemirli, Fatma;Dimoglo, Anatholy;Reynolds, Robert. And the article was included in Bioorganic & Medicinal Chemistry in 2005.SDS of cas: 3418-21-1 This article mentions the following:

The preparation of novel 5-aryl-2-thio-1,3,4-oxadiazoles and the computer-aided study of their in vitro antitubercular activity against Mycobacterium tuberculosis H₃₇Rv (ATCC 27294) are reported. The average accuracy of the electronic-topol. method and neural network methods applied to the activity prediction in leave-one-out cross validation is 80%. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1SDS of cas: 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.SDS of cas: 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation and antimycotic properties of derivatives of 1-phenethylimidazole was written by Godefroi, Erik F.;Heeres, Jan;Van Cutsem, Jan;Janssen, Paul A. J.. And the article was included in Journal of Medicinal Chemistry in 1969.Application In Synthesis of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane This article mentions the following:

The synthesis of a large number of β-substituted-1-phenethylimidazoles is described. Many appropriately N-substituted-1-(β-aminophenethyl)imidazoles and cyclic ketals derived from 2-(1-imidazolyl)acetophenones were quite active against dermatophytes. However, 1-(β-benzyloxyphenethyl)-imidazoles displayed potent, broad-spectrum activity, not only against dermatophytes but also against yeast cells (Candida albicans) and gram-pos. bacteria. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Application In Synthesis of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Application In Synthesis of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Cyclopentyl methyl ether-NH₄X: a novel solvent/catalyst system for low impact acetalization reactions was written by Azzena, Ugo;Carraro, Massimo;Mamuye, Ashenafi Damtew;Murgia, Irene;Pisano, Luisa;Zedde, Giuseppe. And the article was included in Green Chemistry in 2015.Synthetic Route of C10H11BrO2 This article mentions the following:

Cyclopentyl Me ether, a low impact ether forming a pos. azeotrope with water, was successfully employed as a solvent in the synthesis of 1,3-dioxanes and 1,3-dioxolanes carried out under Dean-Stark conditions by the acetalization of aliphatic and aromatic aldehydes or ketones, employing ammonium salts as environmentally friendly acidic catalysts. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Synthetic Route of C10H11BrO2).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Synthetic Route of C10H11BrO2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Intramolecular 1,6-hydride transfer in acyclic 1,6-diols: a mechanistic study was written by Gil, Juan F.;Ramon, Diego J.;Yus, Miguel. And the article was included in Tetrahedron in 1994.Product Details of 118336-86-0 This article mentions the following:

The reaction of acyclic 1,6-diol I with 85% phosphoric acid at toluene reflux ketone II through an intramol. 1,6-hydride transfer. This fact is proven by using a deuterated 1,6-diol, in which the corresponding 1,6-deuteride transfer occurs. A mechanistic proposal through a protonated oxepane is formulated, which implies an actual 1,3-hydride transfer; this mechanism differs from the reported one in the literature for cyclic 1,6-diols, in which a real 1,6-hydride transfer takes place due to a proximity effect. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Product Details of 118336-86-0).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Product Details of 118336-86-0

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Arene-catalyzed lithiation reactions with lithium at low temperature was written by Yus, Miguel;Ramon, Diego J.. And the article was included in Journal of the Chemical Society, Chemical Communications in 1991.Name: 2-(4-Chlorobutyl)-1,3-dioxolane This article mentions the following:

The reaction of functionalized alkyl chlorides or Ph sulfides with an excess of lithium powder in the presence of a catalytic amount of an arene (1%; naphthalene, biphenyl, 4,4′-di-tert-butylbiphenyl) in THF at -78° gives the corresponding organolithium compounds, which react with electrophiles such as water, isobutyraldehyde, or cyclohexanone to yield the expected reaction products. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Name: 2-(4-Chlorobutyl)-1,3-dioxolane).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Name: 2-(4-Chlorobutyl)-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis and screening of a new group of fungicides: 1-(2-phenyl-1,3-dioxolan-2-ylmethyl)-1,2,4-triazoles was written by Van Gestel, Jef;Heeres, Jan;Janssen, Marcel;Van Reet, Gustaaf. And the article was included in Pesticide Science in 1980.Application of 3418-21-1 This article mentions the following:

The title triazole fungicides prepared by condensation of substituted phenacyl bromides with vicinal diols, and subsequent treatment of the resulting bromoketals with Na 1,2,4-triazole, were screened for activity against 7 species. E.g., I [71500-05-5] was effective in controlling powdery mildew and barley and in controlling bean rust; it was also systemically active. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Application of 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Application of 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Facile synthesis of enol ethers by cleavage of α-bromoacetals and α-bromoketals mediated by SmI₂ was written by Park, H. S.;Kim, S. H.;Park, M. Y.;Kim, Y. H.. And the article was included in Tetrahedron Letters in 2001.Synthetic Route of C10H11BrO2 This article mentions the following:

Cyclic α-bromo acetals, cyclic α-bromo ketals and cyclic α-bromo thioketals, derived from cyclic and acyclic ketones and aldehydes, reacted with samarium diiodide at -78° in THF to furnish enol ethers or thioenol ethers containing hydroxy or thiol moieties in high yields. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Synthetic Route of C10H11BrO2).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Synthetic Route of C10H11BrO2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem