Day: December 6, 2022

Yu, Hai-Feng published the artcileChemoselective and odorless transthioacetalization of acetals using -oxo-ketene dithioacetals as thiol equivalents, Category: dioxole, the publication is Synthetic Communications (2013), 43(9), 1280-1286, database is CAplus.

Using α-oxo-ketene dithioacetals as odorless thiol equivlents, an efficient and odorless transthioacetalization of acetals has been developed. In the presence of MeCOCl in MeOH, the cleavage of commences to generate thiols at both room and reflux temperatures, and the generated thiols then react with acetals to give correspecting thioacetals e. g., I in good yield. This transthioacetalization is characterized by mild reaction conditions, simple procedure, good yields, and perfect chemoselectivity.

Synthetic Communications published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C9H6FNO2, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Wang, Hong-she published the artcileSynthesis of vanillin 1,2-propylene glycol acetal catalyzed by silica supported perchloric acid, Name: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, the publication is Yingyong Huagong (2013), 42(2), 242-244, database is CAplus.

Vanillin 1,2-propylene glycol acetal was synthesized through the condensation of vanillin with 1,2-propylene glycol using silica supported perchloric acid (HClO₄/SiO₂) as a catalyst. The effects of the molar ratio of reactant, the amount of catalyst, reaction temperature and reaction time on the yield of product were discussed. The results showed that the optimized reaction conditions were as follows: the molar ratio of vanillin (0.1 mol) to 1,2-propylene glycol (0.16 mol) was 1:1.6, the amount of catalyst was 1.5 g, reaction temperature was 80°C, and the reaction time was 45 min. Under the optimum conditions mentioned above, the yield of vanillin 1,2-propylene glycol acetal reached more than 87.1%. HClO₄/SiO₂ as a heterogeneous catalyst had many advantages of high thermal stability, ease of preparation and reusability.

Yingyong Huagong published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C25H47NO8, Name: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Schurig, V. published the artcileEnantiomer analysis by complexation gas chromatography. Scope, merits and limitations, COA of Formula: C6H12O2, the publication is Journal of Chromatography (1988), 441(1), 135-53, database is CAplus.

The application of complexation gas chromatog. in comtemporary enantiomer anal. was investigated. Enantiomers were separated without derivatization on Chiral metal stationary phases, such as manganese(II), cobalt(II), and nickel(II) bis[3-(heptafluorobutanoyl)-(1R)-camphorate], coated on high-resolution glass and fused-silica open-tubular columns. Enantiomeric excesses (ee) up to 99.9% can be precisely determined by complexation gas chromatog. Employing the gas chromatog.-mass spectrometry (single ion monitoring) technique, the determination of ee and absolute configurations of solutes, present in complex mixtures, can be performed at the low picogram level. For the first time, pertinent sources of error in the gas chromatog. determination of ee were identified and novel exptl. verifications thereof are presented. Interconversion profiles due to inversion of configuration during enantiomer separation by complexation gas chromatog. have been detected. Inconsistencies of an empirical quadrant rule, correlating absolute configuration and order of elution of cyclic ethers from nickel(II) bis[3-(heptafluorobutanoyl)-(1R)-camphorate], are reported.

Journal of Chromatography published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C8H7NO4, COA of Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Salomaa, Pentti published the artcileThe kinetics of the uncatalyzed and acid-catalyzed hydrolysis of 1,3-dioxol-4-one and its derivatives. III. Experiments in moderately concentrated acids and in deuterated solvents, Application of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Acta Chemica Scandinavica (1966), 20(5), 1263-72, database is CAplus.

cf. CA 63, 12995c. The rates of hydrolysis of 1,3-dioxolones (I) containing 0, 1, or 2 Me substituents on the C atom between the 2 ether O atoms, in moderately concentrated HCl and in mixtures of light and heavy water, indicate that the I which have no substituents on the C-2 hydrolyze by the normal type of acid-catalyzed ester hydrolysis. The 2-Me-substituted I are not hydrolyzed by either a normal type or an A-1 type ester hydrolysis. It is suggested that a H₂O mol. is involved in the formation of the critical complex. This idea is supported by experiments in light and heavy water and in their mixtures The gross D solvent-isotope effect (kD/k_H = 1.68) is comparable to that found in the normal type of ester hydrolysis, being lower than in A-1 reactions of acetals and acetal-esters. The behavior in H₂O-D₂O mixtures of different compositions conforms to an equation which is based on 3 exchangeable H atoms in the critical complex. A discussion of the hydrolysis mechanism of 2-Me-substituted I is presented.

Acta Chemica Scandinavica published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Application of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Liang, Xuezheng published the artcileSynthesis of novel solid acidic ionic liquid polymer and its catalytic activities, Application of 1,4-Dioxaspiro[4.5]decane, the publication is Kinetics and Catalysis (2013), 54(6), 724-729, database is CAplus.

The novel solid acidic ionic liquid polymer was synthesized through the copolymerization of acidic ionic liquid oligomers and resorcinol-formaldehyde (RF resin). The catalytic activities were studied through the acetalization. The PIL was efficient for the reactions with the average yield over 99.0%. The procedure was quite simple with just one-step to complete both the reactions. The high hydrophobic BET surface, high catalytic activities and high stability gave the PIL great potential for green chem. processes.

Kinetics and Catalysis published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Application of 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Krzymien, M. E. published the artcileGC-MS analysis of organic vapors emitted from polyurethane foam insulation, Quality Control of 1193-11-9, the publication is International Journal of Environmental Analytical Chemistry (1989), 36(4), 193-207, database is CAplus.

The vapors emitted by rigid polyurethane foam at 40 and 80° in dry and in humid (90% relative humidity) air were trapped with a Tenax TA sampling tube and, after thermal desorption, analyzed by high resolution gas chromatog.-mass spectrometry. The chromatograms demonstrate that the qual. composition of the effluent is basically independent of both temperature and humidity of the foam. Over 70 compounds were identified as polyurethane foam off-gases. Among them the most numerous are hydrocarbons. The most abundant is the blowing agent, CFCl₃. The headspace concentration of the majority of them is <10 mg/m³, there are, however, several compounds with concentration >100 mg/m³.

International Journal of Environmental Analytical Chemistry published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Quality Control of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Kankaanpera, Alpo published the artcileStereochemistry of alkyl-1,3-dioxolanes and the kinetics of their hydrolysis, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Turun Yliopiston Julkaisuja, Sarja A: Physico-Mathematica-Biologica (1966), 68 pp., database is CAplus.

Twenty-three methyl substituted 1,3-dioxolanes (disregarding optical isomers) and 23 other substituted 1,3-dioxolanes were prepared for a kinetic study of their hydrolysis. The structures of 25 isomeric derivatives were deduced from kinetic data and, in some cases, the structures of the reagents used in the synthesis. The equilibrium constants of the interconversion of isomers indicate that the 1,3-dioxolane ring is non planar. The exptl. data can be accounted for if the ring has the shape of the half chair of cyclopentane, and one of the hetero atoms is located on the axis of symmetry. The kinetic data reveal that 1,3-dioxolane and its alkyl derivatives are hydrolyzed by the same mechanism as acyclic acetals. The reactions exhibit a number of special features not observed in previous studies of acetal hydrolysis. Structural factors affecting the rates are: polar effects of substituents which influence the strengths of the bonds broken in the rate determining stage, the eclipsing strain resulting from the interaction of substituents at positions 4 and 5 when the critical complex of the hydrolysis is approached, and steric effects due to the bending of substituents at position 2 toward the 1,3-dioxolane ring.

Turun Yliopiston Julkaisuja, Sarja A: Physico-Mathematica-Biologica published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Jia, Wei published the artcileMethod for synthesis of cyclohexanone-ethylene glycol ketal, Application of 1,4-Dioxaspiro[4.5]decane, the publication is Guangdong Huagong (2012), 39(2), 78, 3, database is CAplus.

The paper introduced the use of anhydrous AlCl₃ as catalyst in cyclohexane, with water under the action of with cyclohexanone and ethylene glycol to get cyclohexanone-ethylene glycol ketal, and the specific technol. conditions were discussed.

Guangdong Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Application of 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Islam, Tofazzal Md. published the artcileDynamic rearrangement of F-actin organization triggered by host-specific plant signal is linked to morphogenesis of Aphanomyces cochlioides zoospores, COA of Formula: C16H10O5, the publication is Cell Motility and the Cytoskeleton (2008), 65(7), 553-562, database is CAplus and MEDLINE.

Cochliophilin A (5-hydroxy-6,7-methylenedioxyflavone), a root releasing host-specific plant signal triggers chemotaxis and subsequent morphol. changes in pathogenic Aphanomyces cochlioides zoospores before host penetration. The present study illustrates time-course changing patterns of cytoskeletal filamentous actin (F-actin) organization in the zoospores of A. cochlioides during rapid morphol. changes (encystment and germination) after exposure to cochliophilin A. Confocal laser scanning microscopic anal. revealed that F-actin microfilaments remained concentrated at ventral groove and diffusely distributed in peripheral cytoplasm of the zoospore. These microfilaments dramatically rearranged and changed into granular F-actin plaques interconnected with fine arrays during encystment. A large patch of actin arrays accumulated at one pole of the cystospores just before germination. Then the actin plaques moved to the emerging germ tube where a distinct cap of microfilaments was seen at the tip of the emerging hypha. Zoospores treated with an inhibitor of F-actin polymerization, latrunculin B or motility halting and regeneration inducing compound nicotinamide, displayed different patterns of F-actin in both zoospores and cystospores than those obtained by the induction of cochliophilin A. Collectively, these results indicate that the host-specific plant signal cochliophilin A triggers a dynamic polymerization/depolymerization of F-actin in pathogenic A. cochlioides zoospores during early events of plant-peronosporomycete interactions.

Cell Motility and the Cytoskeleton published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, COA of Formula: C16H10O5.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Islam, M. Tofazzal published the artcileVariation in chemotactic preferences of Aphanomyces cochlioides zoospores to flavonoids, Application In Synthesis of 110204-45-0, the publication is Zeitschrift fuer Naturforschung, C: Journal of Biosciences (2009), 64(11/12), 847-852, database is CAplus and MEDLINE.

The zoospores of the phytopathogenic Aphanomyces cochlioides are chemotactically attracted by a host-specific flavone, cochliophilin A (5-hydroxy-6,7-methylenedioxyflavone), and repelled from the mammalian estrogens or estrogenic compounds This study further examined the responses of A. cochlioides zoospores to some flavonoids structurally related to cochliophilin A or compounds known as phytoestrogens. The bioassay revealed that some synthetic flavones (such as 6-methyl-4′-methoxyflavone, 3-hydroxy-4′-methoxyflavone, 7-hydroxy-5-methylflavone, 3-hydroxy-4′-methoxy-6-methylflavone) elicited attractant activity at concentrations as low as picomolar (10 pM), which was an 100-fold lower concentration than that of the threshold concentration of the host-specific attractant cochliophilin A. Apparently, a hydrophobic B-ring with an alkylated (methylated) A-ring or a methoxylated B-ring with an unsubstituted A-ring in the flavone skeleton played a significant role in higher attractant activity. On the other hand, all known estrogenic flavonoids (such as equol, 3′- or 8-prenylated naringenins) displayed potent repellent activity toward zoospores. Surprisingly, zoospores were attracted by non-estrogenic 6-prenylated naringenin indicating that repellent activity is linked to the estrogenic activity of the phytoestrogens.

Zeitschrift fuer Naturforschung, C: Journal of Biosciences published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, Application In Synthesis of 110204-45-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem